FROM DATA TO INSIGHT
OUR VISION
At HighPeak Bioinformatics, we believe that the full potential of next-generation sequencing can only be realized through robust, tailored data analysis. Our mission is to empower scientists to gain deeper insights into their biological systems. We provide you with high-quality analytical solutions so you can focus on the biology.
OUR APPROACH
Your project is supported by a dedicated bioinformatician who works closely with you to define questions, analyze data, and interpret results. They can focus solely on analytics or contribute more broadly to your research, including meetings, seminars, and student mentoring.
Deliverables are tailored to your needs, and every project includes fully reproducible RMarkdown reports with all code, analyses, and results.
OUR SERVICES
Alignment, basic processing and quality control
Analysis of data quality and all standard processing steps: Triming of adaptors, alignment to a reference genome, peak calling, generation of count-matrices, etc.
Downstream analysis to answer biological questions
Analysis of differential expression/ binding/accessibility, dimensionality reduction, assingment of cell identities, pathway analysis and more!
Data mining
We can help you find and analyze other relevant datasets. Integrating them with your data can put it into context and generate novel insights!
Figures and writing
We have extensive experience building compelling and professional figures for your publications and reports. We also can help you write the descritpion of the results and methods.
Integration of different data types
How do differentially expressed genes relate to the binding sites of your protein? Do the changes in chromatin accesibility result in changes in expression? Combination of different types of experimental data is where NGS-based experiments shine to produce molecular insights!
Building data analysis pipelines
Do you want to automate the initial analysis steps of frequently-used a technique? We can help you build an automated analysis pipeline that will speed up the analysis in your lab for years!
Training
We can provide one-on-one training to members of your team
Consulting
We can advice you and your team on different aspects of data analysis, statistics and experimental design
TECHNIQUES
Building of analysis pipelines (Snakemake)
Bulk and single-cell ATAC-seq
Generation of graphic user interfaces to explore data (Shiny-Apps)
Genomic binding profiling techniques (CUT&RUN, CUT&Tag, ChIP-Seq)
Chromatin states models
Proteomics (SILAC and label-free, IP-MS, Organelle proteomics)
Bulk and single-cell
RNA-seq
Data-mining
Molecular biology related to NGS experiments
Get in Touch
Do you have NGS data from which you think you could get more insight? Or you have a project which could maybe benefit from NGS approaches? Talk to us! Our scientists would love to advise you on your project and how we could help you with your biological questions!